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| 2007 |
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Summer 2007
(Vol. 25 No. 3) |
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• Isentris 3.0—Combining your own data with data from commercial or reference sources
• Isentris 3.0—Taking the drudgery out of scientific reporting
• Spain's National Cancer Research Center improves pharmacological profiling with DiscoveryGate
• ACD/Labs calculators in MDL Draw
• MathSpec partnership accelerates identification of structures in mass spectral data |
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Spring 2007
(Vol. 25 No. 2) |
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• MDL® Assay Explorer® at Daiichi Pharmaceutical
• Rgroup decomposition using Isentris for Excel
• Improved chemical sourcing with MDL® Isentris
• Migrating to Isentris with a Starter Kit
• Handling metabolic transformations with Isentris
• Building a query/browse application with Isentris controls
• Elsevier acquires the Beilstein Database
• 2007 European Users' Group Meeting |
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Winter 2007
(Vol. 25 No. 1) |
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• Lars Barfod on boosting productivity with MDL® Isentris®
• Reducing the information bottleneck
• The new-generation MDL® Draw
• Integrating workflows with MDL® Notebook
• Custom development with MDL® Isentris® controls
• Gold-standard chemistry searching with MDL® Direct
• Accessing Excel® spreadsheets in MDL® Assay Explorer®
• DiscoveryGate® adoption accelerating in academia |
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| 2006 |
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Fall 2006
(Vol. 24 No. 4) |
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• Connecting with customers: Enhanced communications and services
• MDL® Isentris® 2.0 update
• MDL® ACD at Merck-Frosst Canada
• MDL® Assay Explorer® at Acumen
• DiscoveryGate® content linked with GeneGo databases
• Top-ranked universities adopt DiscoveryGate
• European Users' Group Meeting and CSA Trust
• Elsevier MDL OHS and GHS standards compliance
• Investigating reaction mechanisms at University of Cambridge
• MDL drawing packages adopted by Prous Integrity® portal |
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Summer 2006
(Vol. 24 No. 3) |
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• Milan's Recordati transitions to MDL® Isentris® with positive results
• Accelerating synthesis planning using full reaction schemes on DiscoveryGate®
• Finding new compounds fast with MDL® sourcing databases
• MDL® Patent Chemistry Database-Feedback and continuing enhancements
• MDL® Registration-Best registration practices for organizations of all sizes
• MDL® Notebook-Integrating content and workflow, enhancing ease-of-use
• Beilstein database exceeds ten million reactions
• VP Doug Hounshell on content development |
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Spring 2006
(Vol. 24 No. 2) |
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• Chemical representation/reaction searching capabilities of MDL® Notebook
• Involving customers in product design through usability testing
• Linking DiscoveryGate® and the NIH PubChem database
• Enhancements to MDL® Available Chemicals Directory
• More about PharmaPendium™, The Essential Drug Safety Resource
• Faster, easier structure and query drawing with MDL® Draw 2.0
• Upgrading the MDL® CrossFire Direct server
• Integration improvements with MDL® Logistics 1.1
• Elsevier MDL in Tokyo
• MDL® Assay Explorer at the Scripps Research Institute
• Senior VP Vikki Rehn on Framework Development |
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Winter 2006
(Vol. 24 No. 1) |
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Chinese researchers harness MDL® content in fight against SARS…Accessing a wealth of drug safety data with PharmaPendium™…Investigating product availability with DiscoveryGate® and the value of retrosynthetic schemes in synthesis planning…Using your preferred analysis and visualization tools with MDL® Assay Explorer® … Accelerating SAR analysis with MDL® Isentris®… Managing your compound registry with MDL® Registration …Utilizing chemical structure and text queries with MDL® DocSearch™…Introducing the new Elsevier MDL corporate headquarters…CEO Lars Barfod on our technology and customer initiatives for 2006 |
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| 2005 |
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Fall 2005
(Vol. 23 No. 4) |
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Trevor Heritage, Sr. VP Workflow Business Group, on integrating the discovery interface … DiscoveryGate® in a university lab…MDL® Isentris 1.4…Dynamic data access with Isentris…MDL® ISIS Server 5.1 product suite…MDL® Isentris Alliance update… DiscoveryGate on Mac OS X…Bridging textual and structural data…DiscoveryGate "Also found in" links…Elsevier MDL OHS and OHS Platinum Service… Elsevier MDL Informatics Fellowship at Indiana University…Introducing "The Pink Sheet" and "Pink Sheet" DAILY…A new book from Elsevier, "Drug Discovery: from Bedside to Wall Street" by Tamas Bartfai & Graham V. Lees. |
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Special Isentris Edition
(September 2005) |
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MDL® Isentris® and Isentris Alliance: Introduction and overview…Isentris workflow solutions (MDL® Logistics, MDL® Plate Manager, MDL® Notebook)…Integration of chemistry and biology data (Viewing screening data and image data)…Desktop integration (Integrating with Microsoft® Excel/PowerPoint and Spotfire® DecisionSite®, Drilling down to biological data)…Platform integration (Transferring chemical structures to DiscoveryGate®, Accessing document repositories with MDL® DocSearch)…Solutions for chemists (Integrating chemical calculators, Rgroup decomposition, Clustering hit lists, Enumerating generic reactions, Annotating corporate data)…Isentris success stories (Custom registration at Intervet, Compound acquisition at Johnson & Johnson) |
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Summer 2005
(Vol. 23 No. 3) |
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MDL® Assay Explorer® and other MDL® technology at Stanford’s High-Throughput Biosciences Center…Improved data warehousing on the Isentris® platform…Bioactivity profiling with MDL® Patent Chemistry Database…Structure-linking and querying between custom applications and the DiscoveryGate® service…An update on the new MDL Notebook® ELN…The new train-the-trainer program…Online ordering of selected products…Successful executive briefings and User meetings in the U.S. and Europe. |
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Spring 2005
(Vol. 23 No. 2) |
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DSM Nutritional Products builds a new chemical inventory management system...The value of MDL Isentris to R&D management...Analyzing curve-fit data with MDL Base…Reaction searching with MDL Patent Chemistry Database…The new DiscoveryGate: Faster, simpler, easier to use…The new MDL Assay Explorer: Improved performance and integration…The new MDL Isentris curriculum…An overview of Customer Care. |
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Winter 2005
(Vol. 23 No. 1) |
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Intervet builds a custom registration system on MDL Isentris...MDL Direct on CatalysisNet.com...Informatics strategies for start-ups...Patent searching in MDL Patent Chemistry Database...Overview of first European Content Day...Expanded reaction searching...Introducing the MDL Isentris Alliance...Upcoming user group meetings...Latest recipient of Informatics Fellowship at Indiana University...PharmaDiscovery 2005 (an Elsevier Event)...Scientific Advisory Board meets in California...The new Elsevier MDL Learning Center...CEO Lars Barfod on the MDL Isentris advantage. |
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| 2004 |
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Fall 2004
(Vol. 22 No. 4) |
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Johnson & Johnson builds a compound acquisition system using MDL Isentris... Amphioxus evaluates structure-toxicity relationships with MDL Assay Explorer... Reagent sourcing with MDL Discovery Logistics... The new MDL Patent Chemistry Database… Redesigned MDL CrossFire Commander 7.0... CrossFire Commander training at Penn... Integrating biology and chemistry informatics with MDL Select... Configuring data sources with the Isentris Data Source Builder... New, self-paced training modules for MDL CrossFire Commander and DiscoveryGate... Four new, online review journals from Drug Discovery Today... David Hughes on bringing Elsevier MDL solutions to market... In the News: MDL Isentris licensed by Novo Nordisk and Boehringer Ingelheim; MDL Carcinogenicity Module licensed by Novo Nordisk; MDL Assay Explorer Visualizer now available. |
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Summer 2004
(Vol. 22, No. 3) |
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Unveiling MDL® Isentris™... The Integrating Data Source: A new network model for accessing and presenting data... Enhancing project team collaboration and productivity with Isentris... MDL® Discovery Logistics: Reagent sourcing and management on the Isentris platform... MDL® Draw in the Isentris client tier... Organon's successful transition to EMSCOPES, the customized bibliographic data solution from Elsevier... Customers at Norak Biosciences and the University of Arkansas benefit from MDL Web Workshops... Introducing the Elsevier Current Opinion and Trends journals... Recent executive changes at MDL and Elsevier's Science & Technology Board... a roundup of the 2004 user group meetings. |
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Spring 2004
(Vol. 22, No. 2) |
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Discovery Partners International improve efficiencies with MDL® Report Manager... Speedel Experimenta accelerate workflows with MDL solutions… MDL's restructured Consulting organization... At the bench with MDL® Plate Manager... DiscoveryGate(SM) for academia... Introducing xPharm(SM)... Extending MDL reaction-linking capabilities... Improving R&D efficiencies with MDL® Isentris™... Elsevier's Tetrahedron journals... Introducing the Biopendium™ database... Maximizing the value of MDL solutions with MDL® Open Library |
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Winter 2004
(Vol. 22, No. 1) |
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AstraZeneca uses MDL® Direct to build a proprietary, structure-searchable compound database... New approaches to meeting customer needs from Elsevier Life Sciences Business... In the News: Agreements with BASF, Organon, and VWR International... Scientific Advisory Board assesses computing power and integration in discovery informatics... MDL donates CrossFire Beilstein and CrossFire Gmelin licenses to the St. Petersburg State Institute of Technology... A new chemistry registration domain service from MDL... DiscoveryGateSM: Mining bioactivity and metabolism/toxicology databases for compounds to treat Alzheimer's disease... DiscoveryGate: Saving researchers' time and planning synthetic routes... Simplifying sample management with MDL® Plate Manager... Improving registration and workflow integration with MDL® ChemBio AE 2.0... Introducing MDL® Assay Explorer Visualizer... Customer-requested enhancements drive upgrades to MDL server products. |
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| 2003 |
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Fall 2003
(Vol. 21, No. 4) |
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Memory Pharmaceuticals accelerates neuropharmaceutical drug development with MDL® Assay Explorer. CEO Bernard Aleva discusses expanding the scope of data integration. MDL receives a Lilly Global Supplier Award. Introducing BIOSILICO, a new Elsevier publication for the pharma/biotech market. MDL Consulting stresses the importance of business integration in discovery informatics. Fast, intuitive pharmacological profiling using DiscoveryGateSM. Introducing MDL® Isentris™ and MDL® Base. New integration enhancements with MDL® Draw. MDL® Metabolite surpasses 10,000 compounds. MDL® Carcinogenicity Module reduces drug development time, cost, and risk. |
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Summer 2003
(Vol. 21, No. 3) |
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MDL, a significant player in the new Elsevier Life Sciences division, welcomes Bernard Aleva as new CEO. Customers find DiscoveryGate(SM) to be an easy, cost-effective way to access MDL® Available Chemicals Directory. MDL® Carcinogenicity Module is the first in a series of predictive software modules, developed in collaboration with the FDA, that will provide reliable toxicology predictions based on chemical structures. Explore MDL® Decision Manager—a shared, collaborative workspace for evaluating data and testing ideas. |
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Spring 2003
(Vol. 21, No. 2) |
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MDL announces a regorganization of its global consulting and customer service organization. Learn about the new strategic alliance with SciTegic, and the first meeting of the Scientific Advisory Board. Read about the chemical registration systems on the job at Allergan and Aventis. |
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Winter 2003
(Vol. 21, No.1) |
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This year MDL celebrates 25 years of leadership in discovery informatics. The phase we're in today is something like the first quarter moon - an impressive sight transitioning to something even grander. As we progress to
the next phase, MDL informatics solutions will reflect an even greater amount of light, revealing more of the discovery domain. |
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| 2002 |
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Fall 2002
(Vol. 20, No.3) |
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Responding to customers, One place to go for the answers you need, DiscoveryGate®, Measuring customer satisfaction and expanding a popular Web forum
MDL® Assay Explorer, Bringing researchers and data together, MDL® Core Interface 1.0 |
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Summer 2002
(Vol. 20, No.2) |
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MDL launches a new look at ACS Orlando - and a new grad student at Indiana University. MDL takes charge of the RTECS database and plays a lead role in the Conference on Chemical Structures.
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Spring 2002
(Vol. 20, No.1) |
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MDL products and services are making a difference in innovative customer initiatives-from Molecular Music's method for "listening to protein structures" to integrated information networks at Merck KGaA and NiKem Research Srl. |
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| 2000 |
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Winter 2000
(Vol. 19, No.2) |
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Globally, MDL customers have begun the migration process from the molecule gateway to the Relational Chemical Gateway. Are you one of them? Learn from customers what to expect - and how to make your migration successful. |
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Spring 2000
(Vol. 19, No.1) |
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Behind any innovative research program or sophisticated data mining application lies solid, validated chemical content. This Special Report introduces some of MDL's latest
content products and describes how five customers are using MDL databases to support forward-looking research in drug design. |
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| 1999 |
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Fall 1999
(Vol. 18, No.4) |
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Prospecting for New Products: Structural Data Mining,
MDL Customers Think SMART, New Bioactivity Databases |
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Summer 1999
(Vol. 18, No.3) |
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The Web is cool. But is it the right tool to support your researchers? We talked to MDL consultants about how to build successful Web-based discovery applications. |
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Spring 1999
(Vol. 18, No.2) |
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Without a doubt, Spotfire offers an entirely new way of analyzing data. We talk to some usability gurus about the ideas behind Spotfire and the future of scientific software development. |
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Winter 1999
(Vol. 18, No.1) |
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Oxymoron or not, companies have discovered that succeeding in discovery means failing compounds-the earlier, the better. |
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| 1998 |
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October 1998
(Vol. 17, No.4) |
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High-throughput chemistry challenges scientists and organizations by complicating workflows and logistics. Learn about how two new tools from MDL can help you regain control over the process. |
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July 1998
(Vol. 17, No.3) |
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Customers Link Robotics and MDL Software, MDL Addresses the Year 2000 Issue, Automation in the Discovery Lab. |
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April 1998
(Vol. 17, No.2) |
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Toward a Component Architecture, A Tale of Two Systems at Bayer AG, Taking Stock of Inventory Management |
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